Urinary but Not Brain Isatin Levels Are Reduced in Germ-Free Rats

Autor: Vivette Glover, John M. Halket, M. Sandier, Marie E. Coates, A. Przyborowska, P.J. Watkins
Rok vydání: 1991
Předmět:
Zdroj: Journal of Neurochemistry. 57:1074-1075
ISSN: 1471-4159
0022-3042
Popis: Germ-free rats excreted considerably smaller amounts of the monoamine oxidase-inhibiting compound isatin than the substantially larger output by conventional animals of the same strain, although concentrations in brain and other tissues were similar in the two groups. Thus, isatin is likely to be elaborated both endogenously in rat tissues and "exogenously" by flora inhabiting the lumen of the alimentary tract.
Databáze: OpenAIRE