Expression of glycoprotein gp43 in stage-specific forms and during dimorphic differentiation of Paracoccidioides brasiliensis
| Autor: | Rosália Santos Amorim Jesuino, M O Azevedo, Maristela Pereira, Maria Sueli Soares Felipe, Silvia Maria Salem-Izacc, R. Mattar-Filho, J.L. Gesztesi, W.A. Brito, Renata de Bastos Ascenço Soares, C. M. A. Soares |
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| Rok vydání: | 1997 |
| Předmět: |
Antigens
Fungal Blotting Western Morphogenesis Oligosaccharides Microbiology Fungal Proteins Gene expression Humans Electrophoresis Gel Two-Dimensional Stage specific skin and connective tissue diseases Mycelium Glycoproteins Paracoccidioides brasiliensis chemistry.chemical_classification biology Paracoccidioides General Medicine biology.organism_classification Yeast Sexual dimorphism Molecular Weight Infectious Diseases chemistry Electrophoresis Polyacrylamide Gel Paracoccidioidomycosis Glycoprotein |
| Zdroj: | Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology. 35(5) |
| ISSN: | 0268-1218 |
| Popis: | Expression of the 43 kDa glycoprotein (gp43) was analysed in several Paracoccidioides brasiliensis isolates. Using one- and two-dimensional analysis of crude cellular extracts, it was shown that protein expression in yeast and mycelium was dependent on the isolate analysed. In two strains, in both yeast and mycelium cells, gp43 was present, whereas expression was restricted to the yeast phase of two other strains. The clinical implications of this phase-specific gp43 expression are uncertain. |
| Databáze: | OpenAIRE |
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