Polyphenol-rich extract of Salvia chinensis exhibits anticancer activity in different cancer cell lines, and induces cell cycle arrest at the G₀/G₁-phase, apoptosis and loss of mitochondrial membrane potential in pancreatic cancer cells
Autor: | Rui‑Qian Dong, Xue‑Chen Huo, Fu‑Dong Sun, Quan Zhao |
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Rok vydání: | 2014 |
Předmět: |
Cancer Research
Cell Survival Salvia chinensis Apoptosis Biology Biochemistry fluorescence microscopy Cell cycle phase salvianolic acid B chemistry.chemical_compound Cell Line Tumor Genetics medicine Humans Propidium iodide Viability assay Salvia Molecular Biology Cell Proliferation Membrane Potential Mitochondrial Cell growth Plant Extracts Cancer Polyphenols Articles Cell cycle medicine.disease HCT116 Cells Molecular biology Antineoplastic Agents Phytogenic G1 Phase Cell Cycle Checkpoints Cell biology Retraction Pancreatic Neoplasms Oncology chemistry cell cycle arrest Cancer cell MCF-7 Cells Molecular Medicine DNA Damage |
Zdroj: | Molecular Medicine Reports |
ISSN: | 1791-3004 |
Popis: | Pancreatic cancer (PC) is one of the most aggressive types of human malignancy, which has an overall 5-year survival rate of |
Databáze: | OpenAIRE |
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