Detection of hepatitis C virus (HCV) among health care providers in an Egyptian university hospital: different diagnostic modalities
| Autor: | Rehab H. El-Sokkary, Rehab M. Elsaid Tash, Eman M. Mortada, Takwa E Meawed, Omnia S. El Seifi |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
OraQuick HCV Pediatrics medicine.medical_specialty Hepatitis C virus medicine.disease_cause Diagnostic modalities Serology 03 medical and health sciences 0302 clinical medicine Saliva testing Health care medicine Infection control Pharmacology (medical) Original Research Pharmacology biology business.industry Public health virus diseases infection control ROC curve digestive system diseases 030104 developmental biology Infectious Diseases Infection and Drug Resistance 030220 oncology & carcinogenesis HCV biology.protein Antibody business |
| Zdroj: | Infection and Drug Resistance |
| ISSN: | 1178-6973 |
| DOI: | 10.2147/idr.s145844 |
| Popis: | Rehab H El-Sokkary,1 Rehab M Elsaid Tash,1 Takwa E Meawed,1 Omnia S El Seifi,2 Eman M Mortada2 1Medical Microbiology and Immunology Department, 2Community, Environmental and Occupational Medicine Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt Background: Hepatitis C virus (HCV) infection has received much attention and is placed at the core of the infection control agenda. It is considered as a major public health problem in Egypt, where the highest prevalence of HCV exists. The great risk of exposure to infection of health care providers (HCPs) has highlighted the urgent need for implementing an infection control program. Objective: The purpose of this study was to detect the prevalence of HCV infection among HCPs in Zagazig University Hospitals and to assess the performance of different diagnostic modalities.Methodology: Blood, polymerase chain reaction (PCR), enzyme-linked immunosorbent assay (ELISA), and saliva tests were performed in enrolled HCPs.Results: This study compared HCV diagnosis Hepanostika HCV Ultra ELISA as a screening test and PCR as gold standard test, which resulted in 40.6% positive results by ELISA compared to 34.8% by PCR (p |
| Databáze: | OpenAIRE |
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