Improvement of depth dose distribution using multiple-field irradiation in boron neutron capture therapy
Autor: | Masaru Narabayashi, Hiroki Tanaka, Yoshinori Sakurai, Natsuko Kondo, Yuko Kinashi, Tsubasa Watanabe, Koji Ono, Shin-ichiro Masunaga, Yoshiaki Nakagawa, Minoru Suzuki, Takushi Takata, Akira Maruhashi, N. Fujimoto |
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Rok vydání: | 2015 |
Předmět: |
inorganic chemicals
Nuclear reaction Dose-volume histogram Radiation Materials science business.industry medicine.medical_treatment chemistry.chemical_element Boron Neutron Capture Therapy Radiotherapy Dosage Radiation therapy Neutron capture chemistry Head and Neck Neoplasms medicine Humans Distribution (pharmacology) Neutron Irradiation Nuclear medicine business Boron |
Zdroj: | Applied Radiation and Isotopes. 106:134-138 |
ISSN: | 0969-8043 |
DOI: | 10.1016/j.apradiso.2015.07.041 |
Popis: | It is important that improvements are made to depth dose distribution in boron neutron capture therapy, because the neutrons do not reach the innermost regions of the human body. Here, we evaluated the dose distribution obtained using multiple-field irradiation in simulation. From a dose volume histogram analysis, it was found that the mean and minimum tumor doses were increased using two-field irradiation, because of improved dose distribution for deeper-sited tumors. |
Databáze: | OpenAIRE |
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