Mitogauzone, cisplatin, and vinblastine in advanced non-small cell lung cancer: A Southwest Oncology Group study
| Autor: | Ben Lin Hom, Robert Chapman, Joel G. Lucas, Harry E. Hynes, John Crowley, Clarence B. Vaughn, Robert B. Livingston |
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| Rok vydání: | 1993 |
| Předmět: |
Adult
Male Oncology medicine.medical_specialty Lung Neoplasms Mitoguazone medicine.medical_treatment Vinblastine Carcinoma Non-Small-Cell Lung Internal medicine Antineoplastic Combined Chemotherapy Protocols medicine Humans Pharmacology (medical) Lung cancer Aged Neoplasm Staging Pharmacology Response rate (survey) Cisplatin Chemotherapy business.industry Respiratory disease Drugs Investigational Middle Aged medicine.disease Toxicity Female business medicine.drug |
| Zdroj: | Investigational New Drugs. 11:91-92 |
| ISSN: | 1573-0646 0167-6997 |
| DOI: | 10.1007/bf00873920 |
| Popis: | This trial employing MGBG, vinblastine, and cisplatin in patients with advanced NSCLC produced a 10% response rate with no durable responses. This is disappointing compared to previously cited studies, although the median overall survival of 7.0 months is comparable. The relatively mild toxicity noted in this trial suggests that more aggressive use of the same combination may be feasible. |
| Databáze: | OpenAIRE |
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