Rare case of uterine neoplasm: cervical sarcoma with endometrial carcinoma
Autor: | Jie-Qiong Cao, Yan Yin, Ying Ma, Ye Zhao, Qiu-Man Wang, Xiao Han, Li-Ting Yao |
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Rok vydání: | 2019 |
Předmět: |
Pathology
medicine.medical_specialty Medicine (General) Case Report endometrial carcinoma Hysterectomy Biochemistry Uterine neoplasm abnormal vaginal bleeding 03 medical and health sciences 0302 clinical medicine R5-920 Pregnancy Rare case Carcinoma Medicine Humans Uterine Neoplasm 030219 obstetrics & reproductive medicine business.industry Biochemistry (medical) Sarcoma Cell Biology General Medicine Middle Aged medicine.disease Endometrial Neoplasms 030220 oncology & carcinogenesis Uterine Neoplasms immunohistochemistry Immunohistochemistry Female pathology business multiple primary malignant tumors cervical sarcoma |
Zdroj: | The Journal of International Medical Research Journal of International Medical Research, Vol 48 (2020) |
ISSN: | 1473-2300 |
Popis: | Multiple primary malignant tumors (MPMTs) refer to two or more primary malignant neoplasms that simultaneously or successively occur in one or more organs in the same individual. Cervical sarcoma concomitant with endometrial carcinoma is rare. A 46-year-old woman was admitted because of increased menstrual volume for 4 years and irregular vaginal bleeding with discharge for 6 months. The diagnosis of endometrial carcinoma at stage II was made on the basis of results of ultrasound, pelvic magnetic resonance imaging, and hysteroscopic curettage. Extensive total abdominal hysterectomy + bilateral adnexectomy + bilateral ovarian arteriovenous high ligation + pelvic adhesion separation + pelvic lymphadenectomy +abdominal aortic lymphadenectomy via the abdomen were performed. Postoperative diagnosis of cervical sarcomas with endometrial carcinoma in stage IIIC1 was made according to the results of pathology and immunohistochemistry. Six cycles of cisplatin-epirubicin-isocyclophosphamide treatment were provided after the operation. Most clinical manifestations of cervical sarcomas are abnormal vaginal bleeding. Use of preoperative imaging and hysteroscopy is difficult for diagnosing cervical sarcomas, and postoperative pathological examinations and immunohistochemical diagnosis are mainly used instead. The possibility of MPMTs should be considered for endometrial carcinoma, especially if the cervical lesion is larger than that of the uterine cavity. |
Databáze: | OpenAIRE |
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