Jejunal fibroplasia in a rat
| Autor: | Masao Hamamura, Kazufumi Kawasako, Takeshi Kanno |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty 040301 veterinary sciences 0403 veterinary science Jejunum Lesion 03 medical and health sciences Eosinophilic medicine Animals rat Trichrome stain jejunum General Veterinary biology Chemistry fibroplasia Jejunal Diseases 04 agricultural and veterinary sciences Fibroblasts Note Fibrosis Rats 030104 developmental biology medicine.anatomical_structure Cytoplasm biology.protein Mitotic Figure Immunohistochemistry Antibody medicine.symptom |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.16-0566 |
| Popis: | A jejunal nodular mass was identified in an aging rat. Histologically, the boundaries between the lesion and surrounding normal tissue as well as between the inner circular muscle and outer longitudinal muscle were indistinct. The lesion consisted of abundant eosinophilic matrix and cells with a large round to oval nucleus and indistinct cytoplasm. There was no characteristic proliferating pattern, nuclear polymorphism and a low mitotic figure count. Masson's trichrome stain revealed that the intestinal smooth muscles were replaced by the abundant collagen fiber. Immunohistochemistry revealed that the cells with a large round to oval nucleus were labeled with anti-vimentin antibody and not with anti-α smooth muscle actin antibody, suggesting that these cells were fibroblasts. The mass was diagnosed as jejunal fibroplasia. |
| Databáze: | OpenAIRE |
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