Pea Albumin 1 Subunit b (PA1b), a Promising Bioinsecticide of Plant Origin

Autor: Lamis Karaki, Corinne Royer, Pedro Da Silva, Vanessa Eyraud, Frédéric Gressent
Přispěvatelé: Biologie Fonctionnelle, Insectes et Interactions (BF2I), Institut National de la Recherche Agronomique (INRA)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon, We thank V. James for the English corrections. The work on PA1b in Lyon was supported by Region Centre and Rhone-Alpes, by the IFR41, the ANR and INSA-Lyon. We would like to pay special homage to the late Bernard Delobel, who first discovered the insecticidal property of PA1b., Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA), Gressent, Frederic
Jazyk: angličtina
Rok vydání: 2011
Předmět:
moustique
0106 biological sciences
Insecticides
Insecta
insecte nuisible
Health
Toxicology and Mutagenesis
legumes
lcsh:Medicine
Peptide
Review
Insect
01 natural sciences
media_common
2. Zero hunger
chemistry.chemical_classification
0303 health sciences
biology
Sitophilus
food and beverages
Biodiversity
Organic farming
toxicology
aphide
media_common.quotation_subject
Protein subunit
Molecular Sequence Data
Structure-Activity Relationship
03 medical and health sciences
PA1b
insect
bioinsecticide
aedes aegypti
Albumins
Botany
Culex pipiens
Animals
Amino Acid Sequence
Pest Control
Biological
030304 developmental biology
Aedes
Base Sequence
lcsh:R
fungi
Peas
toxicologie
biology.organism_classification
Protein Subunits
chemistry
PEST analysis
humain
010606 plant biology & botany
[SDV.EE.IEO]Life Sciences [q-bio]/Ecology
environment/Symbiosis
Zdroj: Toxins
Toxins, MDPI, 2011, 3 (12), pp.1502-17. ⟨10.3390/toxins3121502⟩
Toxins 12 (3), 1502-1517. (2011)
Toxins, Vol 3, Iss 12, Pp 1502-1517 (2011)
ISSN: 2072-6651
DOI: 10.3390/toxins3121502⟩
Popis: International audience; PA1b (Pea Albumin 1, subunit b) is a peptide extract from pea seeds showing significant insecticidal activity against certain insects, such as cereal weevils (genus Sitophilus), the mosquitoes Culex pipiens and Aedes aegyptii, and certain species of aphids. PA1b has great potential for use on an industrial scale and for use in organic farming: it is extracted from a common plant; it is a peptide (and therefore suitable for transgenic applications); it can withstand many steps of extraction and purification without losing its activity; and it is present in a seed regularly consumed by humans and mammals without any known toxicity or allergenicity. The potential of this peptide to limit pest damage has stimulated research concerning its host range, its mechanism of action, its three-dimensional structure, the natural diversity of PA1b and its structure-function relationships.
Databáze: OpenAIRE
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