Identification of differentially expressed microRNAs in middle-size ovarian follicles of Meishan and Duroc sows
Autor: | Cheng-Yi Song, Zhi-Chao Zhao, Xiao-Yan Wang, Da-Quan Li, Ya-Yin Qi, Tao Li, Huang Tao, Lipeng Ma |
---|---|
Rok vydání: | 2019 |
Předmět: |
endocrine system
040301 veterinary sciences media_common.quotation_subject Biology SF1-1100 Mapk signaling pathway 0403 veterinary science Andrology middle-sized follicles microRNA Follicular phase sow medicine KEGG Ovarian follicle Gene Ovulation media_common 0402 animal and dairy science 04 agricultural and veterinary sciences 040201 dairy & animal science Animal culture medicine.anatomical_structure follicular phase Gene chip analysis Animal Science and Zoology differentially expressed miRNA |
Zdroj: | Revista Brasileira de Zootecnia v.48 2019 Revista Brasileira de Zootecnia Sociedade Brasileira de Zootecnia (SBZ) instacron:SBZ Revista Brasileira de Zootecnia, Volume: 48, Article number: e20170326, Published: 28 NOV 2019 Revista Brasileira de Zootecnia, Vol 48 (2019) |
ISSN: | 1806-9290 1516-3598 |
Popis: | This study aimed to investigate the roles of miRNA in the development of ovarian follicles in sows with high ovulation rate. The miRNA expression profiles in middle-size ovarian follicles between Meishan and Duroc sows were characterized by Affymetrix miRNA GeneChip. Seven differentially expressed miRNA were identified. KEGG pathways analyzed the predicted target genes of differentially expressed miRNA by using the DAVID website. The MAPK signaling pathway may affect the process of ovarian follicle development. Our study suggested that miR-21, miR-199a, miR-708, and miR-4334 might play a vital role in the development of ovarian follicles of sow. |
Databáze: | OpenAIRE |
Externí odkaz: |