Genetic diversity of respiratory enteroviruses and rhinoviruses in febrile adults, Singapore, 2007‐2013
| Autor: | Celeste M. Donato, Gavin J. D. Smith, Miguel L. Grau, Marcus G. Mah, Jenny G. Low, Martin Linster, Dhanasekaran Vijaykrishna, Eng Eong Ooi, Yvonne C. F. Su |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine Serotype Adolescent Fever Rhinovirus febrile illness Epidemiology virus diversity Primary care 030312 virology Biology medicine.disease_cause Young Adult 03 medical and health sciences Short Article Enterovirus Infections medicine Humans Respiratory system Phylogeny Aged Enterovirus Retrospective Studies Singapore 0303 health sciences Genetic diversity Picornaviridae Infections Phylogenetic tree phylogenetic analysis Public Health Environmental and Occupational Health Genetic Variation Febrile illness Short Articles Middle Aged respiratory system Virology 3. Good health serotypes Infectious Diseases Female Seasons human activities |
| Zdroj: | Influenza and Other Respiratory Viruses |
| ISSN: | 1750-2659 1750-2640 |
| Popis: | To understand the genetic diversity and patterns of circulation of rhinoviruses (RV) and enteroviruses (EV) in Singapore, we retrospectively screened 2950 nasal swab samples collected from adults presenting to primary care services with signs of febrile illness in Singapore during 2007‐2013 using sequencing and phylogenetic methods. Through sequencing and phylogenetic analysis, our results show the year‐round circulation of the three rhinovirus species, A, B, and C. A diverse set of RV/EV serotypes were detected in Singapore with a predominance of RV‐A in all years, whereas serotypes EV‐C A21 and EV‐D68 were only sporadically detected. This study highlights the previously unrecognized diversity and burden in the adult population in Singapore. |
| Databáze: | OpenAIRE |
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