Hepatic infarction in a hemodialysis patient with systemic lupus erythematosus
| Autor: | Donna Lager, Michael Abecassis, Bruce Kaplan, Jane L. Cooper |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Systemic disease medicine.medical_treatment Gastroenterology immune system diseases Renal Dialysis Internal medicine medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases Lupus anticoagulant Lupus erythematosus Vascular disease business.industry medicine.disease Connective tissue disease Thrombosis Lupus Nephritis Liver Nephrology Acute abdomen Infarction Antibodies Anticardiolipin Lupus Coagulation Inhibitor Hemodialysis medicine.symptom business |
| Zdroj: | American journal of kidney diseases : the official journal of the National Kidney Foundation. 26(5) |
| ISSN: | 0272-6386 |
| Popis: | Hepatic infarction remains a rare and dramatic presentation of an acute abdomen in patients with systemic lupus erythematosus. It can be recognized preoperatively only with a high index of suspicion. Imaging studies such as abdominal computed tomography may aid in making the diagnosis. The tendency for thrombosis in these patients often can be associated with the presence of circulating anticoagulants from a group of antiphospholipid antibodies. The finding of lupus anticoagulant or anticardiolipin antibodies can help identify those patients more prone to thrombotic episodes, although at present it cannot be assumed that these antibodies cause the thromboses. Hemodialysis patients are said to have a decreased tendency for vascular thrombosis, but this may not be true in the presence of circulating antiphospholipid antibodies. We report a case of histologically documented hepatic infarction secondary to thrombosis in an end-stage renal disease patient on hemodialysis with systemic lupus erythematosus and a circulating lupus anticoagulant. |
| Databáze: | OpenAIRE |
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