Fabrication of a novel electrochemical immunosensor for the sensitive detection of carcinoembryonic antigen using a double signal attenuation strategy

Autor:	Xiao Wang, Xiaochen Liao, Bingjian Zhang, Siyu Chen, Mengmeng Zhang, Lisha Mei, Li Zhang, Xiuwen Qiao, Chenglin Hong
Rok vydání:	2022
Předmět:	Immunoassay Polymers Iron Metal Nanoparticles Biosensing Techniques Naphthols Electrochemical Techniques Hydrogen Peroxide Silicon Dioxide Biochemistry Ferric Compounds Analytical Chemistry Carcinoembryonic Antigen Peroxidases Limit of Detection Environmental Chemistry Gold Spectroscopy
Zdroj:	Analytica chimica acta. 1232
ISSN:	1873-4324
Popis:	Carcinoembryonic antigen (CEA), an acidic protein, is a characteristic antigen produced by the tumor of various cancers (eg, breast, cervical, rectal, lung, etc.). Therefore, the detection of cancer antigens is very important for the early diagnosis and treatment of cancer. In this study, a novel of "signal off" strategy for electrochemical immunosensor was developed to detect CEA. To this end, Prussian blue nanoparticles (PB NPs), an electroactive substance, were used as the immunological platform. In addition, CuO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc518844c4518fd7dbd5ada7b7733d5f https://pubmed.ncbi.nlm.nih.gov/36257740 Zobrazit plný text záznamu Full Text from ScienceDirect