Fifteen years of HIV and syphilis outcomes among a prevention of mother-to-child transmission program in Haiti: from monotherapy to Option B
| Autor: | Myung Hee Lee, Jerry Bonhomme, Vanessa Rouzier, Elaine J. Abrams, Julma Pierrot, Jean W. Pape, Deanna Jannat-Khah, Marie Marcelle Deschamps, Margaret L. McNairy |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Maternal-Child Health Services Human immunodeficiency virus (HIV) Psychological intervention HIV Infections Hiv testing medicine.disease_cause Retrospective data 03 medical and health sciences Young Adult Pregnancy Syphilis testing Prenatal Diagnosis Outcome Assessment Health Care medicine Humans Syphilis Pregnancy Complications Infectious Hiv transmission Retrospective Studies Obstetrics business.industry Public Health Environmental and Occupational Health Infant Newborn virus diseases Prevention of mother to child transmission Prenatal Care medicine.disease 030112 virology Haiti Infectious Disease Transmission Vertical Infectious Diseases Parasitology Female business Program Evaluation |
| Zdroj: | Tropical medicineinternational health : TMIH. 23(7) |
| ISSN: | 1365-3156 |
| Popis: | OBJECTIVE To evaluate mother and infant outcomes in the largest prevention of mother-to-child-transmission (PMTCT) programme in Haiti in order to identify gaps towards elimination of HIV and syphilis. METHODS Based on retrospective data from HIV+ pregnant women and their infants enrolled in PMTCT care from 1999 to 2014, we assessed maternal enrolment in PMTCT, receipt of antiretrovirals before delivery, maternal retention through delivery as well as infant enrolment in PMTCT, HIV testing and HIV infection. Four PMTCT programme periods were compared: period 1 (1999-2004, mono ARV), period 2 (2005-2009, dual ARV), period 3 (2010-2012, Option B) and period 4 (Oct 2012-2014, Option B+). Kaplan-Meier methods were used to assess retention in PMTCT care. RESULTS Among 4665 pregnancies, median age was 27 years and median CD4+ was 494 cells/μl (IQR 328-691). A total of 75% of women received antiretrovirals before delivery, and 73% were retained in care through delivery. Twenty-two percent of women were lost before delivery |
| Databáze: | OpenAIRE |
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