Molecular mechanisms for pharmacological effects of drugs based on Cimicifuga racemosa extracts

Autor:	N P Lapochkina, O A Gromova, L. E. Fedotova, I.Yu. Torshin, N K Tetruashvili
Jazyk:	ruština
Rok vydání:	2018
Předmět:	Klimaktoplan N Traditional medicine cimicifuga Chemistry Cimicifuga racemosa Obstetrics and Gynecology sanguinaria climacterium lcsh:Gynecology and obstetrics lcsh:RG1-991 sepia
Zdroj:	Гинекология, Vol 20, Iss 1, Pp 39-46 (2018)
ISSN:	2079-5831 2079-5696
Popis:	An estrogen-like activity is considered to be the main mechanism of action for Cimicifuga extract. At the same time, results of modern studies of molecular composition together with modern fundamental data indicate such critical mechanisms of action as activation of serotoninergic and GABA-ergic ways of neurotransmission, as well as anti-inflammatory and antidiabetic effects. The use of drugs based on C. racemosa extracts is perspective for accompanying replacement hormonal therapy with estrogens due to antineoplastic and osteoprotective effects of standardized C. racemosa extracts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbde802c0c4f3c0a6a233dea2227a18a http://gynecology.orscience.ru/en/archive/2018/vol-20-1-2018/8_2834/?element Zobrazit plný text záznamu