Diagnostic precision of image-guided multisampling core needle biopsy of suspected lymphomas in a primary care hospital
| Autor: | Pierre Loubeyre, Thomas Alexander Mckee, Antoine Rosset, Pierre-Yves Dietrich, Michele Copercini |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Lymphoma Hospitals core needle biopsy Malignancy ddc:616.0757 Biopsy Site Recurrence hemic and lymphatic diseases Biopsy Medicine Humans Lymphoma/*diagnosis/*surgery molecular analysis Grading (tumors) Molecular Diagnostics Aged ddc:616 Primary Health Care Aged 80 and over medicine.diagnostic_test business.industry Benignity Biopsy Needle Anatomical pathology Middle Aged medicine.disease Subtyping Surgery Oncology Female Radiology business |
| Zdroj: | British Journal of Cancer British Journal of Cancer, Vol. 100, No 11 (2009) pp. 1771-1776 |
| ISSN: | 1532-1827 0007-0920 |
| Popis: | We evaluated the diagnostic quality of image-guided multisampling core needle biopsy (CNB) in patients investigated for suspected lymphoma in a primary care hospital. A total of 112 patients were consecutively assessed during a 3-year period. There were 80 lymphoid site biopsies and 32 non-lymphoid site biopsies. Eight to nine cores were obtained from different parts of the biopsy site. Two cores were systematically frozen, allowing for further morphological, immunochemistry and molecular studies. The diagnostic yield of CNB for malignancy was 100%. Only 47% (41/87) of patients with initial suspicion of lymphoma were finally diagnosed with Lymphoma. The diagnostic yield of CNB for lymphoma typing was 98% (62/63), according to the WHO classification. The diagnostic yield of CNB for complete lymphoma subtyping/grading was 86% (54/63). The diagnostic yield of CNB for a definite diagnosis of benignity was only 47% (8/17). In a primary care setting, multisampling CNB is a minimally invasive, and very accurate procedure for confirming malignancy in patients with suspected lymphoma, presenting with superficial/deep-seated, lymphoid/non-lymphoid site targets. With a very high diagnostic yield for lymphoma typing and a high diagnostic yield for complete lymphoma subtyping/grading a therapeutic decision can be taken in most patients. |
| Databáze: | OpenAIRE |
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