Prognostic value and clinical predictors of intramyocardial hemorrhage measured by CMR T2* sequences in STEMI

Autor: Anastasio Montero-Argudo, José Luis Díez-Gil, Diego Plaza-López, Maria Ferré-Vallverdú, Begoña Igual-Muñoz, Carolina Gil-Cayuela, Pilar Sepúlveda-Sanchis, Vicente Miró-Palau, Luis Martínez-Dolz, E. Sánchez-Lacuesta, Alicia Maceira-Gonzalez
Rok vydání: 2020
Předmět:
Zdroj: The international journal of cardiovascular imaging. 37(5)
ISSN: 1875-8312
Popis: Recent studies show that microvascular injury consists of microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH). In patients with reperfused ST-segment elevation myocardial infarction (STEMI) quantitative assessment of IMH with T2* cardiovascular magnetic resonance imaging (CMR) appears to be useful in evaluation of microvascular damage. The current study aimed to investigate feasibility of this approach and to correlate IMH with clinical and CMR parameters. A single center observational cohort study was performed in reperfused STEMI patients with CMR examination 7 days (IQR: 5 to 8 days) after percutaneous coronary intervention. Infarct size (IS) and MVO were evaluated in short-axis late gadolinium enhancement sequences and IMH with whole LV volume T2* mapping sequences. Of the 94 patients, MVO was identified in 52% of patients and the median size of MVO was 3% of LV mass (IQR: 1.5 to 5.4%). IMH was present in 28% of patients and the median size of IMH was 1.1% of LV mass (IQR: 0.5 to 2.9%). IMH extent was independently associated with anterior myocardial infarction (p = 0.022) and thrombectomy (p = 0.049). IMH was correlated with MVO (R = 0.62, p
Databáze: OpenAIRE