Lifetime Care of Duchenne Muscular Dystrophy
| Autor: | Joshua O. Benditt, Maida L. Chen, E MacKintosh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
musculoskeletal diseases
Duchenne muscular dystrophy Pediatrics medicine.medical_specialty congenital hereditary and neonatal diseases and abnormalities Central sleep apnea Neuromuscular disease Polysomnogram Respiratory failure Article 03 medical and health sciences 0302 clinical medicine medicine Insomnia Humans biology business.industry Chronic pain General Medicine medicine.disease Obstructive sleep apnea nervous system diseases Muscular Dystrophy Duchenne Psychiatry and Mental health Clinical Psychology Neuropsychology and Physiological Psychology 030228 respiratory system Insomnia hypoventilation biology.protein Disease Progression Neurology (clinical) medicine.symptom business Dystrophin Noninvasive ventilation 030217 neurology & neurosurgery |
| Zdroj: | Sleep Medicine Clinics |
| ISSN: | 1556-4088 1556-407X |
| Popis: | Individuals with Duchenne muscular dystrophy (DMD) have evolving sleep and respiratory pathophysiology over their lifetimes. Across the lifespan of DMD, various sleep-related breathing disorders (SRBD) have been described, including obstructive sleep apnea, central sleep apnea, and nocturnal hypoventilation. In addition to SRBD, individuals with DMD can be affected by insomnia, chronic pain and other factors interfering with sleep quality, and daytime somnolence. The natural progression of DMD pathophysiology has changed with the introduction of therapies for downstream pathologic pathways and will continue to evolve with the development of therapies that target function and expression of dystrophin. |
| Databáze: | OpenAIRE |
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