Child and adult spinal tuberculosis at tertiary hospitals in the Western Cape, South Africa: 4-year burden and trend
Autor: | Robert P. Lamberts, H S Schaaf, R. N. Dunn, J. du Toit, Theresa N. Mann, S Dix-Peek, K du Preez, Johan H. Davis |
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Rok vydání: | 2018 |
Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Tuberculosis Adolescent Epidemiology Kyphosis Corrective surgery Spinal disease Tertiary Care Centers 03 medical and health sciences South Africa Young Adult 0302 clinical medicine Cost of Illness medicine Prevalence Humans Child Retrospective Studies 030222 orthopedics Original Paper business.industry Public health Infant Odds ratio Middle Aged medicine.disease Confidence interval Infectious Diseases Child Preschool Western cape Female Tuberculosis Spinal business 030217 neurology & neurosurgery |
Zdroj: | Epidemiology and infection. 146(16) |
ISSN: | 1469-4409 |
Popis: | The aim of this retrospective review was to assess the overall burden and trend in spinal tuberculosis (TB) at tertiary hospitals in the Western Cape Province of South Africa. All spinal TB cases seen at the province's three tertiary hospitals between 2012 and 2015 were identified and clinical records of each case assessed. Cases were subsequently classified as bacteriologically confirmed or clinically diagnosed and reported with accompanying clinical and demographic information. Odds ratios (OR) for severe spinal disease and corrective surgery in childvs.adult cases were calculated. A total of 393 cases were identified (319 adults, 74 children), of which 283 (72%) were bacteriologically confirmed. Adult cases decreased year-on-year (P= 0.04), however there was no clear trend in child cases. Kyphosis was present in 60/74 (81%) children and 243/315 (77%) adults with available imaging. Corrective spinal surgery was performed in 35/74 (47%) children and 80/319 (25%) adults (OR 2.7, 95% confidence interval 1.6–4.5,P= 0.0003). These findings suggest that Western Cape tertiary hospitals have experienced a substantial burden of spinal TB cases in recent years with a high proportion of severe presentation, particularly among children. Spinal TB remains a public health concern with increased vigilance required for earlier diagnosis, especially of child cases. |
Databáze: | OpenAIRE |
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