Occipital pilomyxoid astrocytoma in a 14-year-old girl – case report
| Autor: | Antonio Taddei, Daniela Moncini, Francesca Castiglione, Maio, Lorenzo Genitori, Chiara Francesca Gheri, Francesca Garbini, Gianluigi Taddei, Massimiliano Sanzo, Annamaria Buccoliero |
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| Rok vydání: | 2008 |
| Předmět: |
Pilomyxoid astrocytoma
Pathology medicine.medical_specialty Adolescent Population Astrocytoma Pathology and Forensic Medicine Lesion Eosinophilic medicine Adjuvant therapy Humans education High rate education.field_of_study medicine.diagnostic_test Brain Neoplasms business.industry Magnetic resonance imaging General Medicine medicine.disease Neurology Female Occipital Lobe Neurology (clinical) medicine.symptom business |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 0722-5091 |
| DOI: | 10.5414/npp27373 |
| Popis: | Pilomyxoid astrocytoma is a recently described tumor. Its most typical morphological characteristics are an angiocentric astrocytic proliferation embedded in a myxoid background. The behavior seems to be unfavorable due to the reported high rate of local recurrence. The earlier studies indicated that pilomyxoid astrocytoma typically affects young children and arises in the hypothalamic/chiasmatic region. We report a case of a 14-year-old patient with a 6-year history of absence seizure. Magnetic resonance imaging showed a right occipital lesion of approximately 3 cm in diameter. The patient underwent the surgical procedure with gross total excision. Histologically, the tumor was mainly composed of a monomorphous population of bipolar elongated piloid cells radially arranged around thin-walled blood vessels in a prominent myxoid background. There were focal hemorrhagic foci but no bona fide evidence of tumor necrosis or mitoses. Rosenthal fibers and eosinophilic granular bodies were not observed. The postoperative course was uneventful. No adjuvant therapy was administered. The patient is alive and well at 18-month follow-up. The case presented provides evidence that pilomyxoid astrocytoma can occur at a later age and can arise in regions different from hypothalamic/chiasmatic. |
| Databáze: | OpenAIRE |
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