Transition-metal-free Synthesis of tetra-substituted Vinyl Iodides by Cascade Sequential Reaction of α-Keto Acids, 1-Iodoalkynes, and Alkyl Halides

Autor: Xiaobao Zeng, Zhenfeng Cheng, Yushan Xie, Yunhui Gu
Rok vydání: 2022
Předmět:
Zdroj: Chemistry, an Asian journal.
ISSN: 1861-471X
Popis: The cascade sequential reaction of α-keto acids, 1-iodoalkynes, and alkyl halides are reported herein to synthesize tetra-substituted vinyl iodides. It represents an efficient protocol to access a diverse range of tetra-substituted vinyl iodides starting from simple materials in a one-pot fashion, featuring mild reaction conditions, ease of operation, and broad substrate scope.
Databáze: OpenAIRE