Fluid resuscitation management in patients with burns: update
Autor: | Gemma Usua, Juan P. Barret, Patricia Guilabert, Maria J. Colomina, Nuria Martin, Luis Abarca |
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Rok vydání: | 2016 |
Předmět: |
Parkland formula
medicine.medical_specialty Resuscitation business.industry Haemodynamic monitoring Crystalloid solutions 030208 emergency & critical care medicine Crystalloid Solutions Increased capillary permeability 03 medical and health sciences 0302 clinical medicine Anesthesiology and Pain Medicine Fluid therapy Pharmacovigilance Fluid Therapy Humans Medicine In patient Colloids 030212 general & internal medicine Isotonic Solutions Burns business Intensive care medicine |
Zdroj: | British Journal of Anaesthesia. 117:284-296 |
ISSN: | 0007-0912 |
DOI: | 10.1093/bja/aew266 |
Popis: | Since 1968, when Baxter and Shires developed the Parkland formula, little progress has been made in the field of fluid therapy for burn resuscitation, despite advances in haemodynamic monitoring, establishment of the ‘goal-directed therapy' concept, and the development of new colloid and crystalloid solutions. Burn patients receive a larger amount of fluids in the first hours than any other trauma patients. Initial resuscitation is based on crystalloids because of the increased capillary permeability occurring during the first 24 h. After that time, some colloids, but not all, are accepted. Since the emergence of the Pharmacovigilance Risk Assessment Committee alert from the European Medicines Agency concerning hydroxyethyl starches, solutions containing this component are not recommended for burns. But the question is: what do we really know about fluid resuscitation in burns? To provide an answer, we carried out a non-systematic review to clarify how to quantify the amount of fluids needed, what the current evidence says about the available solutions, and which solution is the most appropriate for burn patients based on the available knowledge. |
Databáze: | OpenAIRE |
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