Novel coronavirus epidemic in the Hungarian population, a cross-sectional nationwide survey to support the exit policy in Hungary
| Autor: | Gergő Merkely, Júlia Karády, Béla Merkely, János Sinkó, Kornélia Mag, Attila Szabo, Annamaria Kosztin, József Betlehem, Csaba Papp, Barna Vásárhelyi, Endre Ludwig, Gyula Prinz, Csaba Lengyel, Péter Varga, István Várkonyi, Ildikó Csóka, Gabor A. Fulop, Ervin Berényi, Balázs Hankó, Zoltán Vokó, Andor Sebestyén, Katalin Burián, Attila Miseta |
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| Rok vydání: | 2020 |
| Předmět: |
Aging
Cross-sectional study Pneumonia Viral Population Sample (statistics) Severe Acute Respiratory Syndrome medicine.disease_cause Serology Betacoronavirus 03 medical and health sciences 0302 clinical medicine Cross-sectional Surveys and Questionnaires medicine Humans Young adult Social isolation education Pandemics Sampling frame 030304 developmental biology Coronavirus Hungary 0303 health sciences education.field_of_study SARS-CoV-2 business.industry COVID-19 Ageing Cross-Sectional Studies Nationwide Original Article Geriatrics and Gerontology medicine.symptom Coronavirus Infections business 030217 neurology & neurosurgery Demography |
| Zdroj: | GeroScience |
| ISSN: | 2509-2723 2509-2715 |
| DOI: | 10.1007/s11357-020-00226-9 |
| Popis: | After months of restrictive containment efforts to fight the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) epidemic, European countries are planning to reopen. To support the process, we conducted a cross-sectional survey among the Hungarian population to estimate the prevalence of infectious cases and prior SARS-CoV-2 exposure. A representative sample (n = 17,787) for the Hungarian population of 14 years or older living in private households (n = 8,283,810) was selected. The study was performed within 16 days after 50 days of restrictions, when the number of confirmed cases was stable low. Naso- and oropharyngeal smears and blood samples were collected for PCR and antibody testing. The testing was accompanied by a questionnaire about symptoms, comorbidities, and contacts. Design-based prevalence estimates were calculated. In total, 10,474 individuals (67.7% taken into account a sample frame error of 2315) of the selected sample participated in the survey. Of the tested individuals, 3 had positive PCR and 69 had positive serological test. Population estimate of the number of SARS-CoV-2 infection and seropositivity were 2421 and 56,439, respectively, thus active infection rate (2.9/10,000) and the prevalence of prior SARS-CoV-2 exposure (68/10,000) was low. Self-reported loss of smell or taste and body aches were significantly more frequent among those with SARS-CoV-2. In this representative, cross-sectional survey of the Hungarian population with a high participation rate, the overall active infection rate was low in sync with the prevalence of prior SARS-CoV-2 exposure. We demonstrated a potential success of containment efforts, supporting an exit strategy. NCT04370067, 30.04.2020. |
| Databáze: | OpenAIRE |
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