Bioorthogonal micellar nanoreactors for prodrug cancer therapy using an inverse-electron-demand Diels-Alder reaction

Autor:	Fumi Suehiro, Shota Fujii, Tomoki Nishimura
Rok vydání:	2022
Předmět:	Cycloaddition Reaction Metals and Alloys Electrons General Chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Mice Heterocyclic Compounds Neoplasms Materials Chemistry Ceramics and Composites Animals Nanotechnology Prodrugs Micelles
Zdroj:	Chemical communications (Cambridge, England). 58(50)
ISSN:	1364-548X
Popis:	Micellar nanoreactors based on the self-assembly of an IEDDA reactive unit bearing amphiphilic polymers are reported. The deployment of the nanoreactors for cancer chemotherapy via prodrug activation by the IEDDA reaction is also demonstrated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa84f5b0d9797f60f4f2fad137665c43 https://pubmed.ncbi.nlm.nih.gov/35642953 Zobrazit plný text záznamu