Increased NHC Cells in the Peritoneal Cavity of Plasmacytoma Susceptible BALB/c Mouse
| Autor: | Berenice Sanchez-Gonzalez, José Eduardo Farfán-Morales, Jiménez-Zamudio L, Francisco Javier García-Vázquez |
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| Rok vydání: | 2015 |
| Předmět: |
Article Subject
BALB/c Mouse Lymphocyte Immunology Inflammation Biology T-Lymphocytes Regulatory C strain Mice chemistry.chemical_compound Peritoneal cavity immune system diseases lcsh:Pathology medicine Animals Lymphocytes Peritoneal Cavity Mice Inbred BALB C Strain (chemistry) Terpenes Pristane T-Lymphocytes Helper-Inducer Cell Biology medicine.disease Molecular biology Mice Inbred C57BL Disease Models Animal medicine.anatomical_structure chemistry Cytokines Th17 Cells Plasmacytoma Female medicine.symptom Oils lcsh:RB1-214 Research Article |
| Zdroj: | Mediators of Inflammation Mediators of Inflammation, Vol 2015 (2015) |
| ISSN: | 1466-1861 0962-9351 |
| Popis: | BALB/c strain mice are unique in that they develop murine plasmacytoma (MPC) as a consequence of the inflammation induced by pristane oil injection in the peritoneal cavity. In this work the Treg, Th17, B1, B2, and NHC lymphocyte populations from the peritoneal environment of BALB/c, the susceptible strain, and C57BL/6 mice, which do not develop MPC after oil treatment, were studied. Both oil-treated strains showed decreased levels of Th17 lymphocytes, no significant variation in Treg lymphocytes, and a drastic decrease of all B lymphocyte populations. However, only oil-induced BALB/c showed increased levels of natural helper cells (NHC) which could be important in the myeloma induction. |
| Databáze: | OpenAIRE |
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