Excellent intubating conditions with remifentanil–propofol and either low-dose rocuronium or succinylcholine
| Autor: | Ghassan E. Kanazi, Reine A. Zbeidy, Samar K. Taha, Badri W. Zahreddine, Mohamad Khatib, Achir A. Al Alami, Marie T. Aouad, Jules-Marie A. Chehade, Sahar M. Siddik-Sayyid, Anis Baraka |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.drug_class medicine.medical_treatment Remifentanil Succinylcholine Vocal Cords Young Adult Double-Blind Method Piperidines Intubation Intratracheal medicine Humans Intubation Androstanols Prospective Studies Muscle paralysis Anesthetics Local Rocuronium Propofol Dose-Response Relationship Drug Laryngoscopy business.industry Low dose Tracheal intubation Lidocaine General Medicine Middle Aged Surgery Anesthesiology and Pain Medicine Elective Surgical Procedures Neuromuscular Depolarizing Agents Anesthesia Sedative Female business Anesthetics Intravenous Neuromuscular Nondepolarizing Agents medicine.drug |
| Zdroj: | Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 56:483-488 |
| ISSN: | 1496-8975 0832-610X |
| Popis: | The shortest time to tracheal intubation, the best intubating conditions, and the shortest duration of muscle paralysis are achieved with succinylcholine. During a lidocaine-remifentanil-propofol induction of anesthesia, we compared intubating conditions 90 s after administering low-dose rocuronium (0.3 mg . kg(-1)) with intubating conditions 60 s after administering succinylcholine 1.5 mg . kg(-1).The randomized double-blind study included 184 healthy adult patients scheduled for elective surgery. Anesthesia was induced in all patients with lidocaine 1.5 mg . kg(-1), remifentanil 2 microg . kg(-1), and propofol 2 mg . kg(-1) administered over 30 s. In one group, rocuronium 0.3 mg . kg(-1) was administered before the induction sequence, and in the other group, succinylcholine 1.5 mg . kg(-1) was administered after the induction sequence. Laryngoscopy was attempted 90 s after rocuronium administration and 60 s after succinylcholine administration. Intubating conditions were assessed as excellent, good, or poor on the basis of ease of laryngoscopy, position of the vocal cords, and reaction to insertion of the tracheal tube and cuff inflation.There were 92 patients per group. In the rocuronium group, intubating conditions were excellent in 83 patients (90%), good in 8 (9%), and poor in 1 (1%), not significantly different from the intubating conditions in the succinylcholine group, which were excellent in 88 patients (96%), good in 3 (3%), and poor in 1 (1%) (P = 0.3).During a lidocaine-remifentanil-propofol induction of anesthesia, rocuronium 0.3 mg . kg(-1) administered before the induction sequence provides intubating conditions comparable to those achieved with succinylcholine 1.5 mg . kg(-1) administered after the induction sequence. |
| Databáze: | OpenAIRE |
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