Synthesis and Application of Silica-Coated Quantum Dots in Biomedicine

Autor: Sungje Bock, Jaehi Kim, Do Won Hwang, Eunil Hahm, Kyeong-Min Ham, Bong-Hyun Jun, Byung Sung Son, Sangtaek Oh, San Kyeong, Yoon-Hee Kim, Seung-min Park, Wooyeon Kim, Sang Hun Lee, Xuan-Hung Pham, Seunho Jung
Rok vydání: 2021
Předmět:
Materials science
Absorption spectroscopy
Surface Properties
QH301-705.5
Biological Availability
Biocompatible Materials
Serum Albumin
Human
Nanotechnology
Review
In Vitro Techniques
Catalysis
Inorganic Chemistry
Mice
Optical imaging
Cell Line
Tumor
Quantum Dots
Biomarkers
Tumor
silica coating
Cell separation
Animals
Humans
Biology (General)
Physical and Theoretical Chemistry
Silica coating
QD1-999
Molecular Biology
Micelles
Spectroscopy
Mice
Inbred BALB C
Optical Imaging
Organic Chemistry
technology
industry
and agriculture
General Medicine
Neoplastic Cells
Circulating
Silicon Dioxide
equipment and supplies
silica encapsulation
Computer Science Applications
bioapplication
Chemistry
Phenotype
quantum dot (QD)
Hydrophobic surfaces
Quantum dot
Surface modification
surface modification
Semiconductor Nanoparticles
Cadmium
Zdroj: International Journal of Molecular Sciences, Vol 22, Iss 10116, p 10116 (2021)
International Journal of Molecular Sciences
ISSN: 1422-0067
DOI: 10.3390/ijms221810116
Popis: Quantum dots (QDs) are semiconductor nanoparticles with outstanding optoelectronic properties. More specifically, QDs are highly bright and exhibit wide absorption spectra, narrow light bands, and excellent photovoltaic stability, which make them useful in bioscience and medicine, particularly for sensing, optical imaging, cell separation, and diagnosis. In general, QDs are stabilized using a hydrophobic ligand during synthesis, and thus their hydrophobic surfaces must undergo hydrophilic modification if the QDs are to be used in bioapplications. Silica-coating is one of the most effective methods for overcoming the disadvantages of QDs, owing to silica’s physicochemical stability, nontoxicity, and excellent bioavailability. This review highlights recent progress in the design, preparation, and application of silica-coated QDs and presents an overview of the major challenges and prospects of their application.
Databáze: OpenAIRE
Externí odkaz: