Differences in hospital length of stay between neonates exposed to buprenorphine versus methadone in utero: A retrospective chart review
| Autor: | Naana Jumah, Teresa Bruni, Brieanne Olibris, Roxanne Turuba, Lisa Bishop, Sarah Fernandez |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Pregnancy
business.industry medicine.disease Confidence interval 03 medical and health sciences 0302 clinical medicine In utero 030225 pediatrics Anesthesia Intensive care Pediatrics Perinatology and Child Health Morphine Medicine Phenobarbital 030212 general & internal medicine Online Only Original Articles business medicine.drug Methadone Buprenorphine |
| Zdroj: | Paediatrics & Child Health. 24:e104-e110 |
| ISSN: | 1918-1485 1205-7088 |
| DOI: | 10.1093/pch/pxy091 |
| Popis: | INTRODUCTION: Neonatal abstinence syndrome is a growing concern in neonatal intensive care units in rural and remote settings. METHODS: A retrospective chart review was conducted of 180 mother–infant dyads born with in utero exposure to buprenorphine (n=60), methadone (n=60) or to other opioids (n=60) to determine neonatal length of stay in hospital, number of days on morphine, day of life of initiation of morphine and the need for phenobarbital. RESULTS: The length of stay in hospital for neonates was 5.8 days shorter (95% confidence interval [CI] 6.1 to 8.5 days) for buprenorphine exposure in utero compared to methadone (P=0.001). For neonates requiring treatment for Neonatal abstinence syndrome, those with in utero exposure to buprenorphine required 6.1 fewer days (95% CI 2.5 to 9.7) of treatment with morphine then those exposed to methadone (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|