Oncologic colorectal surgical site infection: oral or not oral antibiotic preparation, that is the question
| Autor: | Javier Gómez Sánchez, Carlos Garde Lecumberri, Cristina González Puga, Paola de Castro Monedero, Rocío Forneiro Pérez, Benito Mirón Pozo, Marisol Zurita Saavedra |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Cathartics Rectal Neoplasms Colorectal cancer business.industry Gastroenterology Administration Oral Postoperative complication Surgical wound Antibiotic Prophylaxis medicine.disease Total mesorectal excision Anti-Bacterial Agents Surgery Elective Surgical Procedures Preoperative Care medicine Humans Surgical Wound Infection Antibiotic prophylaxis Elective surgery Elective Surgical Procedure business Retrospective Studies Abdominal surgery |
| Zdroj: | International Journal of Colorectal Disease. 37:373-379 |
| ISSN: | 1432-1262 0179-1958 |
| Popis: | PURPOSE Surgical wound infection is the most frequent postoperative complication in abdominal surgery, especially at the colorectal level. The aim of this study is analysing the results of mechanical colon preparation combined with oral antibiotic versus mechanical colon preparation without antibiotic therapy in patients with colorectal cancer undergoing elective surgery. METHODS This retrospective cohort study had been developed from November 2017 to February 2020. We have included a total of 281 consecutive patients undergoing elective colon and rectal oncological surgeries by the same surgical group using laparoscopic and open approaches. Transanal minimally invasive surgery (TAMIS) and transanal total mesorectal excision (TaTME) approaches were excluded. Exposed patients undergoing colon and rectal cancer surgery received mechanical bowel preparation and oral antibiotics with three doses of neomycin 1 g and erythromycin 500 mg the day before surgery. RESULTS The primary outcome was reduction in surgical wound infection rates before and after starting the oral antibiotic therapy from 17 to 6% (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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