Transgenerational gene silencing causes gain of virulence in a plant pathogen
| Autor: | Dinah Qutob, B. Patrick Chapman, Mark Gijzen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Phytophthora
Small RNA Virulence Factors General Physics and Astronomy Virulence General Biochemistry Genetics and Molecular Biology Article Chromosome Segregation Gene silencing Phytophthora sojae Gene Silencing Allele Gene Alleles Crosses Genetic Plant Diseases Genetics Multidisciplinary biology Effector RNA High-Throughput Nucleotide Sequencing General Chemistry biology.organism_classification Phenotype Soybeans |
| Zdroj: | Nature Communications |
| ISSN: | 2041-1723 |
| Popis: | Avirulence (Avr) genes of plant pathogens encode effector proteins that trigger immunity in plants carrying appropriate resistance (R) genes. The Phytophthora sojae Avr3a gene displays allelic variation in messenger RNA transcript levels. P. sojae strains with detectable Avr3a gene transcripts are avirulent on plants carrying the R-gene Rps3a, whereas strains lacking Avr3a mRNA escape detection by Rps3a and are virulent. Here we show non-Mendelian interactions between naturally occurring Avr3a alleles that result in transgenerational gene silencing, and we identify small RNA molecules of 25 nucleotides that are abundant in gene-silenced strains but not in strains with Avr3a mRNA. This example of transgenerational gene silencing is exceptional because it is naturally occurring and results in gain of virulence in a pathogenic organism. Plant pathogens encode effector proteins that trigger immunity in plants carrying appropriate resistance genes. Here Qutob et al. show non-Mendelian interactions between naturally occurring Phytophthora sojae alleles that result in transgenerational gene silencing and gain of virulence in soybean plants. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|