Accuracy of diagnostic imaging modalities for peripheral post-traumatic osteomyelitis – a systematic review of the recent literature
| Autor: | Inge H. F. Reininga, Andor W. J. M. Glaudemans, Geertje A.M. Govaert, Frank F A IJpma, Martin A. McNally, Eugene McNally |
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| Rok vydání: | 2017 |
| Předmět: |
POSITRON EMISSION TOMOGRAPHY
Osteosynthetic material Computed tomography Review Article Scintigraphy 030218 nuclear medicine & medical imaging Ostheosynthesis 0302 clinical medicine 030212 general & internal medicine FDG-PET PROSTHETIC JOINT INFECTION medicine.diagnostic_test Open reduction and internal fixation (ORIF) Osteomyelitis General Medicine Peripheral Radiology Nuclear Medicine and imaging Positron emission tomography Diagnostic imaging Radiology RADIONUCLIDE Antigranulocyte antibody scintigraphy White blood cell scintigraphy MRI LIMITATIONS CT scan medicine.medical_specialty LONG BONES Sensitivity and Specificity IMPLANT-ASSOCIATED INFECTION 03 medical and health sciences medicine Medical imaging Humans Radiology Nuclear Medicine and imaging Fracture related infection METAANALYSIS business.industry Magnetic resonance imaging medicine.disease MUSCULOSKELETAL INFECTIONS Post-traumatic osteomyelitis PET Fracture Bone scintigraphy Wounds and Injuries SCINTIGRAPHY business Nuclear medicine |
| Zdroj: | European Journal of Nuclear Medicine and Molecular Imaging European Journal of Nuclear Medicine and Molecular Imaging, 44(8), 1393. Springer Verlag |
| ISSN: | 1619-7089 1619-7070 |
| Popis: | Aims: Post-traumatic osteomyelitis (PTO) is difficult to diagnose and there is no consensus on the best imaging strategy. The aim of this study is to present a systematic review of the recent literature on diagnostic imaging of PTO. Methods: A literature search of the EMBASE and PubMed databases of the last 16 years (2000–2016) was performed. Studies that evaluated the accuracy of magnetic resonance imaging (MRI), three-phase bone scintigraphy (TPBS), white blood cell (WBC) or antigranulocyte antibody (AGA) scintigraphy, fluorodeoxyglucose positron emission tomography (FDG-PET) and plain computed tomography (CT) in diagnosing PTO were considered for inclusion. The review was conducted using the PRISMA statement and QUADAS-2 criteria. Results: The literature search identified 3358 original records, of which 10 articles could be included in this review. Four of these studies had a comparative design which made it possible to report the results of, in total, 17 patient series. WBC (or AGA) scintigraphy and FDG-PET exhibit good accuracy for diagnosing PTO (sensitivity ranged from 50–100%, specificity ranged from 40–97% versus 83–100% and 51%–100%, respectively). The accuracy of both modalities improved when a hybrid imaging technique (SPECT/CT & FDG-PET/CT) was performed. For FDG-PET/CT, sensitivity ranged between 86 and 94% and specificity between 76 and 100%. For WBC scintigraphy + SPECT/CT, this is 100% and 89–97%, respectively. Conclusions: Based on the best available evidence of the last 16 years, both WBC (or AGA) scintigraphy combined with SPECT/CT or FDG-PET combined with CT have the best diagnostic accuracy for diagnosing peripheral PTO. |
| Databáze: | OpenAIRE |
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