Influence of segmental supply of Cilioretinal artery on morphology of diabetic macular edema

Autor: Rajiv Raman, Rehana Khan, Mahesh P Shanmugam, Niharika Singh, Rajesh Ramanjulu, Avadhesh Oli, Jay Chablani
Rok vydání: 2020
Předmět:
0301 basic medicine
Male
medicine.medical_specialty
genetic structures
Diabetic macular edema
Macular Edema
Retina
03 medical and health sciences
Quadrant (abdomen)
chemistry.chemical_compound
Center involving macular edema
0302 clinical medicine
lcsh:Ophthalmology
Optical coherence tomography
Ophthalmology
medicine
Diabetes Mellitus
Humans
Fluorescein Angiography
Fundus fluorescein angiography
Retrospective Studies
Diabetic Retinopathy
medicine.diagnostic_test
business.industry
Retinal Vessels
Retinal
General Medicine
Diabetic retinopathy
Segmental supply
medicine.disease
ETDRS
eye diseases
Cilioretinal artery
030104 developmental biology
medicine.anatomical_structure
chemistry
lcsh:RE1-994
030221 ophthalmology & optometry
Non-center involving macular edema
Female
business
Retinal thickness
Tomography
Optical Coherence
Research Article
Zdroj: BMC Ophthalmology
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-6 (2021)
ISSN: 1471-2415
Popis: Background The supply of Cilioretinal artery (CRA) to different layers of the retina influences retinal pathologies such as diabetic retinopathy (DR). Since the supply of CRA is segmental, our aim was to analyze the location of CRA with respect to non – center involving diabetic macular edema (DME) differentiated by various segments and center involving DME based on Early Treatment of Diabetic Retinopathy Study (ETDRS) scale using optical coherence tomography (OCT). Methods A retrospective study was conducted in which forty-three patients with various stages of DR and the presence of CRA were identified. Presence and location of CRA was recognized using fundus fluorescein angiography. Classification of DME was based on ETDRS subfields on OCT. Results Evaluation of 26 men and 17 women with varying degrees of severity involving DR revealed the presence of unilateral CRA in 40 subjects and bilateral CRA in 3 subjects. When CRA supplied the central area, maximum retinal thickness was noted at the temporal quadrant (271.67 ± 164.02 μm) along with non - center involving DME (194.87 ± 121.06 μm); when CRA supplied the lower area, maximum retinal thickness was noted at the superior quadrant (293.64 ± 159.36 μm) along with center involving DME (395 ± 285.75 μm) and when it supplied the upper area, maximum retinal thickness was noted at the nasal quadrant (293.49 ± 176.18 μm) along with center involving DME (292 ± 192.79 μm). Conclusion The presence of CRA seems to influence the morphology of the retina amongst patients diagnosed with DR by altering the segments involved in DME based on its supply location. However, further studies with a larger sample size are warranted to strenghten this association.
Databáze: OpenAIRE
Externí odkaz: