Work-related asthma in a sample of subjects with established asthma
| Autor: | Alessandro Ciberti, D Talini, Francesco Di Pede, Paolo Del Guerra, Tonina Enza Iaia, Laura Carrozzi, M Lemmi, Manuela Latorre, D. Bartoli, Pierluigi Paggiaro, A Innocenti |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Pulmonary and Respiratory Medicine medicine.medical_specialty Adolescent Cross-sectional study Population Work related asthma Exacerbations Young Adult 03 medical and health sciences 0302 clinical medicine Occupational hygiene Risk Factors Environmental health Asthma control Prevalence medicine Humans 030212 general & internal medicine Asthma Occupational Workplace education Reimbursement Asthma education.field_of_study business.industry Work-related Dust General population Occupational diseases Occupational exposure Middle Aged medicine.disease Respiratory Function Tests respiratory tract diseases Cross-Sectional Studies Italy 030228 respiratory system Disease Progression Irritants Physical therapy Female business Occupational asthma |
| Popis: | Objective To assess the impact of occupational exposure to irritants or sensitizers on the occurrence, recrudescence and worsening of asthma and to identify unrecognized cases of work related asthma (WRA) including Work-Exacerbated Asthma (WEA) and Occupational Asthma (OA), in a general asthma clinic population sample. Setting, design and participants The study was a population-based cross sectional survey. 1289 asthmatic subjects (from 15 to 46 yrs old) living in a vast district of Tuscany (Italy) were identified from the Medical Reimbursement Register of the National Health System. 893 subjects agreed to take part in the study. Subjects who were currently working or had worked in past were classified in different categories of occupational risk exposure (No, Low or High) according to the italian standard classification for industries and job titles, associated with the judgment of occupational hygiene experts. Results 41% of subjects worked in industries and in job titles at risk for exposure to airway irritants and/or sensitizers, 48.6% reported an occupational exposure to gases, dust and fumes, more males than females. Prevalence of WEA and OA was higher in subjects who worked at higher risk exposure; these subjects reported a higher prevalence of markers of asthma severity (asthma control, level of treatment, FEV1) than subjects without WRA. Risk of WEA was significantly associated to female gender, older age, and self-reported exposure, while risk of OA was associated to job title with higher exposure risk to occupational asthmogens. Conclusions Our study shows a high prevalence of WRA (especially WEA) associated with employment in industries and job titles at risk for airways sensitizers and/or irritants; data also support a role for occupational exposure in determining a poor asthma control and a higher level of asthma severity. |
| Databáze: | OpenAIRE |
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