Osteocyte lacunae in transiliac bone biopsy samples across life span

Autor: Stéphane Blouin, Barbara M. Misof, Matthias Mähr, Nadja Fratzl-Zelman, Paul Roschger, Sonja Lueger, Phaedra Messmer, Petra Keplinger, Frank Rauch, Francis H. Glorieux, Andrea Berzlanovich, Gerlinde M. Gruber, Peter C. Brugger, Elizabeth Shane, Robert R. Recker, Jochen Zwerina, Markus A. Hartmann
Rok vydání: 2023
Předmět:
Zdroj: Acta Biomaterialia. 157:275-287
ISSN: 1742-7061
Popis: Osteocytes act as bone mechanosensors, regulators of osteoblast/osteoclast activity and mineral homeostasis, however, knowledge about their functional/morphological changes throughout life is limited. We used quantitative backscattered electron imaging (qBEI) to investigate osteocyte lacunae sections (OLS) as a 2D-surrogate characterizing the osteocytes. OLS characteristics, the density of mineralized osteocyte lacunae (i.e., micropetrotic osteocytes, md.OLS-Density in nb/mm
Databáze: OpenAIRE