Predictive value of cardiac autonomic indexes and MIBG washout in ICD recipients with mild to moderate heart failure
| Autor: | Efthimios G. Livanis, Vasilios Voudris, Athanasios Katsikis, Peny Flevari, Dimitrios Th. Kremastinos, George N. Theodorakis, M. Georgiadis, Maria Koutelou |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Metabolic Clearance Rate Heart Ventricles Cardiomyopathy Pressoreceptors Baroreflex Autonomic Nervous System Sudden cardiac death Heart Rate Tachycardia Internal medicine medicine Humans Heart rate variability Radiology Nuclear Medicine and imaging Heart Failure Fibrillation Ejection fraction business.industry fungi Heart General Medicine Middle Aged medicine.disease Defibrillators Implantable 3-Iodobenzylguanidine Heart failure Cardiology Female Bolus (digestion) medicine.symptom business |
| Zdroj: | Annals of Nuclear Medicine. 23:677-684 |
| ISSN: | 1864-6433 0914-7187 |
| DOI: | 10.1007/s12149-009-0289-6 |
| Popis: | We aimed at evaluating the combined use of heart rate variability (HRV), baroreflex sensitivity (BRS), and MIBG imaging in the risk stratification for sudden cardiac death (SCD) of patients with mild to moderate heart failure. Twenty-five patients (17 male and 8 female, mean age 63 ± 5 years, mean LVEF 36 ± 3%) with a recently implanted defibrillator (ICD) and mild (NYHA I-II) heart failure due to either ischemic (n = 15) or dilated (n = 10) cardiomyopathy were studied. One week after ICD implantation they underwent (a) baroreflex sensitivity (BRS) evaluation to bolus phenylephrine by the Oxford method, (b) 24-h heart rate variability (HRV) assessment, and (c) MIBG imaging. The mean patient follow-up was 32 ± 10 months. Simple correlation and stepwise multiple regression analysis was performed to evaluate (a) if the number of sustained ventricular tachycardia (cycle length |
| Databáze: | OpenAIRE |
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