Bullous pemphigoid in a 19-year-old woman. A case with unusual target antigens
| Autor: | S. Fujiwara, Hiroshi Hachisuka, Masahiro Kusuhara, Yoichiro Sasai, Osamu Mori |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Exacerbation Blotting Western Dermatology Immunoglobulin E Immunofluorescence Elevated serum Antigen Eosinophilia Pemphigoid Bullous medicine Humans Antigens skin and connective tissue diseases integumentary system biology medicine.diagnostic_test business.industry medicine.disease eye diseases Molecular Weight biology.protein Peripheral Blood Eosinophilia Female sense organs Bullous pemphigoid medicine.symptom business |
| Zdroj: | British Journal of Dermatology. 130:241-245 |
| ISSN: | 1365-2133 0007-0963 |
| Popis: | Summary We report a 19-year-old woman with typical clinical histological and immunofluorescence features of bullous pemphigoid. By immunoblotting, the serum was shown to detect antigens at 240 and 138 kDa. Elevated serum IgK levels were present, and there was a marked peripheral blood eosinophilia. The degree of eosinophilia correlated with small changes in the severity of the skin lesions, and the IgE level showed correlation with marked changes in severity. Another unusual feature was an exacerbation of her disease at the time of her first menses after the onset of the bullous pemphigoid. |
| Databáze: | OpenAIRE |
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