Association Between Intraoperative Blood Glucose and Anastomotic Leakage in Colorectal Surgery
| Autor: | Reudink, M., Huisman, D. E., van Rooijen, S. J., Lieverse, A. G., Kroon, H. M., Roumen, R. M. H., Daams, F., Slooter, G. D., Bleeker, W., Bootsma, B. T., Feo, C. V., van Hoogstraten, M. J., Jongen, A., Komen, N., Lagae, E. A. A. G. L., Sammour, T., Sonneveld, D. J. A., Stassen, L. P. S., Talsma, A. K., Targa, S., Veltkamp, S. C., Verdaasdonk, E. G. G., de Vries Reilingh, T. S., van Wely, B., Reilingh, J. A. W. |
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| Přispěvatelé: | Surgery, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism, VU University medical center, LekCheck Study Group |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Blood Glucose medicine.medical_specialty Surgical stress Anastomosis Anastomotic Leak Anastomotic leakage Colorectal surgery Diabetes mellitus Hyperglycemia Perioperative care Risk factor Aged Anastomosis Surgical Humans Prospective Studies Risk Factors Colorectal Surgery NO 03 medical and health sciences 0302 clinical medicine Surgical medicine business.industry Incidence (epidemiology) Gastroenterology Perioperative medicine.disease Surgery 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Human medicine business Cohort study |
| Zdroj: | Journal of Gastrointestinal Surgery, 25(10), 2619-2627. Springer New York on behalf of the LekCheck study group 2021, ' Association Between Intraoperative Blood Glucose and Anastomotic Leakage in Colorectal Surgery ', Journal of Gastrointestinal Surgery, vol. 25, no. 10, pp. 2619-2627 . https://doi.org/10.1007/s11605-021-04933-2 Journal of Gastrointestinal Surgery |
| ISSN: | 1091-255X |
| DOI: | 10.1007/s11605-021-04933-2 |
| Popis: | Background: Perioperative hyperglycemia is a known risk factor for postoperative complications after colorectal surgery. The aim of this study was to investigate whether intraoperative blood glucose values are associated with colorectal anastomotic leakage in diabetic and non-diabetic patients undergoing colorectal surgery. Methods: This is an additional analysis of a previously published prospective, observational cohort study (the LekCheck study). Fourteen hospitals in Europe and Australia collected perioperative data. Consecutive adult patients undergoing colorectal surgery with primary anastomosis between 2016 and 2018 were included. From all patients, preoperative diabetic status was known and intraoperative blood glucose was determined just prior to the creation of the anastomosis. The primary outcome was the occurrence of anastomotic leakage within 30 days postoperatively. Results: Of 1474 patients (mean age 68 years), 224 patients (15%) had diabetes mellitus, 737 patients (50%) had intraoperative hyperglycemia (≥126 mg/dL, ≥7.0 mmol/L), and 129 patients (8.8%) developed anastomotic leakage. Patients with intraoperative hyperglycemia had higher anastomotic leakage rates compared to patients with a normal blood glucose level (12% versus 5%, P |
| Databáze: | OpenAIRE |
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