MRI in human immunodeficiency virus-associated cerebral vasculitis
| Autor: | Heinrich Lanfermann, W. Enzensberger, Joachim Berkefeld |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Adult
Male Vasculitis Pathology medicine.medical_specialty AIDS Dementia Complex medicine.disease_cause Herpes Zoster Medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Neuroradiology Neurologic Examination medicine.diagnostic_test AIDS-Related Opportunistic Infections business.industry Cerebral infarction Vascular disease Varicella zoster virus Magnetic resonance imaging Cerebral Infarction medicine.disease Magnetic Resonance Imaging Ischemic Attack Transient Carotid artery occlusion cardiovascular system Neurology (clinical) Cerebral Arterial Diseases Cardiology and Cardiovascular Medicine business Cerebral vasculitis Follow-Up Studies |
| Zdroj: | Neuroradiology. 42(7) |
| ISSN: | 0028-3940 |
| Popis: | Cerebral ischaemia caused by inflammatory vasculopathies has been described as complication of human immunodeficiency virus (HIV) infection. Imaging studies have shown ischaemic lesions and changes of the vascular lumen, but did not allow demonstration of abnormalities within the vessel wall itself. Two HIV-infected men presented with symptoms of a transient ischaemic attack. Initial MRI of the first showed no infarct; in the second two small lacunar lesions were detected. In both cases, multiplanar 3-mm slice contrast-enhanced T1-weighted images showed aneurysmal dilatation, with thickening and contrast enhancement of the wall of the internal carotid and middle cerebral (MCA) arteries. These findings were interpreted as indicating cerebral vasculitis. In the first patient the vasculopathy progressed to carotid artery occlusion, and he developed an infarct in the MCA territory, but then remained neurologically stable. In the second patient varicella zoster virus (VZV) infection was the probable cause of vasculitis. The clinical deficits and vasculitic MRI changes regressed with antiviral and immunosuppressive therapy. |
| Databáze: | OpenAIRE |
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