Recruitment methods in a clinical trial of provoked vulvodynia: Predictors of enrollment
| Autor: | Candi C. Bachour, Jim Y. Wan, Candace Brown, Leslie A. Rawlinson, David C. Foster, Gloria Bachmann |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
medicine.medical_specialty Cyclohexanecarboxylic Acids Vulvodynia Ethnic group Article White People 03 medical and health sciences 0302 clinical medicine Ethnicity medicine Humans Mass Media Postal Service 030212 general & internal medicine Amines Socioeconomic status gamma-Aminobutyric Acid Pharmacology Analgesics Clinical Trials as Topic 030219 obstetrics & reproductive medicine Marital Status business.industry Patient Selection Racial Groups Age Factors Chronic pain General Medicine Middle Aged medicine.disease Community-Institutional Relations Black or African American Clinical trial Sexual intercourse Socioeconomic Factors Family medicine Income Physical therapy Educational Status Marital status Household income Female Gabapentin business |
| Zdroj: | Clinical Trials. 14:103-108 |
| ISSN: | 1740-7753 1740-7745 |
| DOI: | 10.1177/1740774516663461 |
| Popis: | Background: Successful recruitment in clinical trials for chronic pain conditions is challenging, especially in women with provoked vulvodynia due to reluctance in discussing pain associated with sexual intercourse. The most successful recruitment methods and the characteristics of women reached with these methods are unknown. Objective: To compare the effectiveness and efficiency of four recruitment methods and to determine socioeconomic predictors for successful enrollment in a National Institutes of Health–sponsored multicenter clinical trial evaluating a gabapentin intervention in women with provoked vulvodynia. Methods: Recruitment methods utilized mass mailing, media, clinician referrals and community outreach. Effectiveness (number of participants enrolled) and efficiency (proportion screened who enrolled) were determined. Socioeconomic variables including race, educational level, annual household income, relationship status, age, menopausal status and employment status were also evaluated regarding which recruitment strategies were best at targeting specific cohorts. Results: Of 868 potential study participants, 219 were enrolled. The most effective recruitment method in enrolling participants was mass mailing ( p Conclusion: In this clinical trial, mass mailing was the most effective recruitment method. Race of participants enrolled in a provoked vulvodynia trial was related to the recruitment method. |
| Databáze: | OpenAIRE |
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