Syntheses, in vitro, and in silico studies of rhodanine-based schiff bases as potential α-amylase inhibitors and radicals (DPPH and ABTS) scavengers

Autor: Samuel Attah Egu, Irfan Ali, Khalid Mohammed Khan, Sridevi Chigurupati, Urooj Qureshi, Uzma Salar, Muhammad Taha, Shatha Ghazi Felemban, Vijayan Venugopal, Zaheer Ul-Haq
Rok vydání: 2022
Předmět:
Zdroj: Molecular Diversity. 27:767-791
ISSN: 1573-501X
1381-1991
Popis: A two-step reaction method was used to synthesize a series of rhodanine-based Schiff bases (2-33) that were characterized using spectroscopic techniques. All compounds were assessed for α-amylase inhibitory and radical scavenging (DPPH and ABTS) activities. In comparison to the standard acarbose (IC
Databáze: OpenAIRE