Factors predicting postoperative morbidity after cytoreductive surgery for ovarian cancer: a systematic review and meta-analysis
Autor: | Malika Kengsakul, Gatske M. Nieuwenhuyzen-de Boer, Suwasin Udomkarnjananun, Stephen J. Kerr, Christa D. Niehot, Heleen J. van Beekhuizen |
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Přispěvatelé: | Gynecological Oncology |
Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: |
Ovarian Neoplasms
Obstetrics and Gynecology General Medicine Cytoreduction Surgical Procedures Carcinoma Ovarian Epithelial Neoadjuvant Therapy Postoperative Complications Oncology SDG 3 - Good Health and Well-being Chemotherapy Adjuvant Humans Female Morbidity Neoplasm Staging Retrospective Studies |
Zdroj: | Journal of Gynecologic Oncology, 33(4):e53. Korean Society of Gynecologic Oncology and Colposcopy |
ISSN: | 2005-0380 |
Popis: | Objective: Advances in ovarian cancer cytoreductive surgery have enabled more extensive procedures to achieve maximal cytoreduction but with a consequent increase in postoperative morbidity and mortality. The aim of this study was to evaluate factors for postoperative morbidity after extensive cytoreductive surgery for primary epithelial ovarian cancer (EOC), particularly those which may be modifiable. Methods: Electronic databases were searched. Meta-analysis was conducted using random-effects models. Results: Fifteen relevant studies, involving 15,325 ovarian cancer patients, were included in this review. Severe 30-day postoperative complications occurred in 2,357 (15.4%) patients. The postoperative mortality rate was 1.92%. Meta-analysis demonstrated that patient with following risk factors; age (p0 (p=0.001), albumin level |
Databáze: | OpenAIRE |
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