Substrate characterization of the right ventricle in repaired tetralogy of Fallot using late enhancement cardiac magnetic resonance
| Autor: | José Rodríguez-Palomares, Gabriel Pascual-González, Alba Santos-Ortega, Antonia Pijuan-Domenech, Nuria Rivas-Gándara, Begoña Benito, Julián Rodríguez-García, Filipa Valente, Laura Dos-Subirà, Ignacio Ferreira-González, Berta Miranda, Blanca Gordon, Jaume Francisco-Pascual, Ferran Rosés-Noguer, Gemma Burcet-Rodriguez, Aida Ribera-Solé, Jordi Pérez-Rodon |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Epicardial Mapping Male Electroanatomic mapping medicine.medical_treatment Ventricular Dysfunction Right Contrast Media Magnetic Resonance Imaging Cine 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Imaging Three-Dimensional Ventricular tachycardia ablation Physiology (medical) Image Interpretation Computer-Assisted Organometallic Compounds Medicine Humans cardiovascular diseases 030212 general & internal medicine Tetralogy of Fallot Late enhancement business.industry Middle Aged Ablation medicine.disease Maximum Voxel medicine.anatomical_structure Ventricle cardiovascular system Female Cardiology and Cardiovascular Medicine business Nuclear medicine Cardiac magnetic resonance Algorithms |
| Zdroj: | Heart rhythm. 18(11) |
| ISSN: | 1556-3871 |
| Popis: | Three-dimensional (3D) substrate characterization by high-resolution late gadolinium enhancement cardiac magnetic resonance (LE-CMR) is useful for guiding ventricular tachycardia ablation of the left ventricle in ischemic heart disease.The purpose of this study was to validate the substrate characterization and 3D reconstruction of LE-CMR images of the right ventricle (RV) in patients with repaired tetralogy of Fallot (rTOF) and to identify the algorithm that best fits with electroanatomic mapping (EAM).RV LE-CMR images were compared with RV EAM in 10 patients with rTOF. RV LE-CMR images were postprocessed and analyzed to identify fibrotic tissue on 3D color maps. The 3D RV substrate reconstructions were created using an adjustable percentage of the maximum voxel signal intensity (MSI) of the scar region to define the threshold between core, transitional zone (TZ), and healthy tissue. Extensions of the core and TZ areas were compared with the scar (0.5 mV) and low-voltage (0.5-1.5 mV) areas obtained by RV EAM. Agreement on anatomic isthmi identification was quantified.The best match between core and scar was obtained at 65% MSI cutoff (mean areas 17.4 ± 9.9 cmThis study demonstrates that characterization of the RV substrate by postprocessing LE-CMR images in rTOF patients is feasible and validates the technique against RV EAM, which could help in planning target ablation. |
| Databáze: | OpenAIRE |
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