A simple simulator to teach enzyme kinetics dynamics. Application in a problem-solving exercise
| Autor: | Guido Santos, Néstor V. Torres |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Science instruction biosciences Computer science business.industry Enzyme kinetics lcsh:LB5-3640 Education problem-solving approach 03 medical and health sciences lcsh:Theory and practice of education 030104 developmental biology 0302 clinical medicine Dynamics (music) Simple (abstract algebra) 030220 oncology & carcinogenesis SIMENKIN business Simulation Biomedicine Michaelis–Menten model Initial rate |
| Zdroj: | Higher Education Pedagogies, Vol 2, Iss 1, Pp 14-27 (2017) |
| ISSN: | 2375-2696 |
| Popis: | Enzyme kinetics is an essential part of biochemistry programs, which have been gaining importance in recent years for their applications in biotechnology and biomedicine. The teaching and learning of these issues has been traditionally hampered by difficulties that stem mainly from the dynamic and mathematical nature of the topic and the introduction of some abstract concepts. In this paper, we propose a simple, home-made application developed in Excel or, alternatively, in Libre Office (SIMENKIN), which allows students to view and interact with the dynamics of enzymatic reactions. The contribution of this specific application stems from the simulation of substrate loss and the associated initial rate of the enzyme catalysed reaction over time, which is not always incorporated into these packages. We illustrate its use applying it in a practical problem-solving approach module, designed to facilitate the learning of the fundamental concepts of enzyme kinetics. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|