Is birth cohort 1985/9–1990/8 a susceptibility window for congenital rubella syndrome in Taiwan?
| Autor: | Ai-Chi Liang, Ping-Hsiu Tsai, Shu Fang Shih, Chen-Li Lin |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Adult
Pediatrics medicine.medical_specialty Adolescent Rubella Syndrome Congenital 030231 tropical medicine Taiwan Antibodies Viral lcsh:Gynecology and obstetrics Rubella City hospital Young Adult 03 medical and health sciences 0302 clinical medicine Seroepidemiologic Studies Obstetrics and Gynaecology Prevalence Humans Medicine 030212 general & internal medicine Child lcsh:RG1-991 Retrospective Studies Pregnancy Congenital rubella syndrome rubella antibodies Immunization Programs business.industry congenital rubella syndrome rubella Infant Obstetrics and Gynecology Outbreak medicine.disease vaccination Vaccination Vaccination policy Child Preschool Disease Susceptibility business Birth cohort Rubella virus pregnant women |
| Zdroj: | Taiwanese Journal of Obstetrics & Gynecology, Vol 55, Iss 3, Pp 368-373 (2016) |
| ISSN: | 1028-4559 |
| DOI: | 10.1016/j.tjog.2016.04.013 |
| Popis: | Objective: The worldwide prevalence of congenital rubella syndrome has drastically decreased after the uptake of vaccine to prevent the infection. However, outbreaks have occurred in some countries due to their own vaccination policies, and this phenomenon has not yet been investigated in Taiwan. Our study aims to fill this gap. Materials and Methods: We constructed an analytical database containing 10,824 pregnant women at the Taipei City Hospital, Taipei, Taiwan from January 2004 to July 2012. They were categorized into five birth cohorts according to the different vaccination programs in Taiwan: those born before 1971; those born between September 1971 and August 1976; between September 1976 and August 1979; between September 1979 and August 1985; and between September 1985 and August 1990. Differences of the seronegative rate and titers were compared using the Chi-square and Kruskal–Wallis tests among the five cohorts. Results: The seronegative rates for the five cohorts were 15.00%, 4.07%, 2.88%, 4.21%, and 10.98%, respectively, and were statistically significant different (p |
| Databáze: | OpenAIRE |
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