An FXPRLamide Neuropeptide Induces Seasonal Reproductive Polyphenism Underlying a Life-History Tradeoff in the Tussock Moth
| Autor: | Kyohei Yoneda, Yoshiomi Kato, Yukiko Senoh, Kunihiro Shiomi, Hiroshi Uehara |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
media_common.quotation_subject
lcsh:Medicine Insect Moths Diapause Polyphenism Bombyx mori Genetics Animals Amino Acid Sequence lcsh:Science Biology Bombyx media_common Multidisciplinary Orgyia biology Evolutionary Developmental Biology Ecology Reproduction lcsh:R Neuropeptides fungi Pupa biology.organism_classification Biological Evolution Neurosecretory Systems Cell biology Insect Hormones Developmental plasticity lcsh:Q Female Seasons Embryonic diapause Gene Function Organism Development Research Article Developmental Biology Neuroscience |
| Zdroj: | PLoS ONE PLoS ONE, Vol 6, Iss 8, p e24213 (2011) |
| ISSN: | 1932-6203 |
| Popis: | The white spotted tussock moth, Orgyia thyellina, is a typical insect that exhibits seasonal polyphenisms in morphological, physiological, and behavioral traits, including a life-history tradeoff known as oogenesis-flight syndrome. However, the developmental processes and molecular mechanisms that mediate developmental plasticity, including life-history tradeoff, remain largely unknown. To analyze the molecular mechanisms involved in reproductive polyphenism, including the diapause induction, we first cloned and characterized the diapause hormone-pheromone biosynthesis activating neuropeptide (DH-PBAN) cDNA encoding the five Phe-X-Pro-Arg-Leu-NH(2) (FXPRLa) neuropeptides: DH, PBAN, and alpha-, beta-, and gamma-SGNPs (subesophageal ganglion neuropeptides). This gene is expressed in neurosecretory cells within the subesophageal ganglion whose axonal projections reach the neurohemal organ, the corpus cardiacum, suggesting that the DH neuroendocrine system is conserved in Lepidoptera. By injection of chemically synthetic DH and anti-FXPRLa antibody into female pupae, we revealed that not only does the Orgyia DH induce embryonic diapause, but also that this neuropeptide induces seasonal polyphenism, participating in the hypertrophy of follicles and ovaries. In addition, the other four FXPRLa also induced embryonic diapause in O. thyellina, but not in Bombyx mori. This is the first study showing that a neuropeptide has a pleiotropic effect in seasonal reproductive polyphenism to accomplish seasonal adaptation. We also show that a novel factor (i.e., the DH neuropeptide) acts as an important inducer of seasonal polyphenism underlying a life-history tradeoff. Furthermore, we speculate that there must be evolutionary conservation and diversification in the neuroendocrine systems of two lepidopteran genera, Orgyia and Bombyx, in order to facilitate the evolution of coregulated life-history traits and tradeoffs. Article PLOS ONE. 6(8):e24213 (2011) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|