Hemodynamic Effects of Pericardial Tamponade

Autor: Shu Chien, Robert J. Dellenback, Robert T. Potter, Magnus I. Gregersen, Shunichi Usami
Rok vydání: 1966
Předmět:
Zdroj: Experimental Biology and Medicine. 123:623-627
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-123-31562
Popis: Discussion and conclusionsThe increase in pericardial and central venous pressures is sufficient to impede venous return to the right atrium and thereby produces a striking drop in cardiac output (Fig. 2). In addition there is a moderate reduction in heart rate during the first 15 minutes of the tamponade (Fig. 2), which also contributes to the reduction in cardiac output. Despite the increase in total peripheral resistance, the reduced blood flow results in an immediate and marked drop in arterial pressure. This decrease activates the baroreceptor mechanisms producing an increase in heart rate which eventually exceeds the control values. The oxygen consumption drops initially because of the reduced blood flow but recovers during the course of the experiment almost to the control value. Since the recovery of oxygen consumption was greater than that of the cardiac output, the oxygen extraction from the blood must have increased, especially in the constant pressure experiments. Coincident with the onset of ...
Databáze: OpenAIRE