Association between insomnia symptoms and cognitive impairment in the Cretan Aging Cohort

Autor: Alexandros N. Vgontzas, Ioannis Zaganas, Antonios Bertsias, Maria Basta, Christos Lionis, Eirini Koutentaki, Maria Anastasaki, Giorgos Mavroidis, George Duijker, Symeon Panagiotakis, Georgia Kalomoiri, Panagiotis G. Simos
Rok vydání: 2018
Předmět:
Zdroj: European Geriatric Medicine. 9:697-706
ISSN: 1878-7657
Popis: Population aging, characteristic of modern Western societies, is associated with various forms of cognitive decline. Insomnia/insomnia-type symptoms have been reported as modifiable risk factors for cognitive decline. The objective of this study was to examine, in a comprehensive way (a) the prevalence and the risk factors associated with insomnia-type symptoms and (b) the association of insomnia-type symptoms with cognitive impairment in a large, homogeneous, community-dwelling population in the island of Crete, Greece. Our sample consisted of 3066 community-dwelling elders aged 60–100 years participating in the Cretan Aging Cohort. All participants were interviewed with a structured questionnaire assessing demographics, physical and mental health, sleep, lifestyle habits and cognitive function using the Mini Mental State Examination (MMSE). Furthermore, insomnia-type symptom prevalence was estimated in the presence of one or more sleep complaints. Linear and logistic regression analyses examined (a) the association between insomnia-type symptoms and demographics, physical/mental health and lifestyle and (b) the association between cognition and insomnia-type symptoms. Prevalence of one or more insomnia-type symptoms was 64.6%. Multivariate analyses showed that female gender, widowhood, benzodiazepine use and physical ailments were significantly associated with insomnia-type symptoms. Multivariate models also showed that insomnia-type symptoms were associated with increased odds of cognitive impairment (p
Databáze: OpenAIRE