Thermal Balloon Angioplasty in a Canine Model: Preliminary Results
| Autor: | Tony P. Smith, Steve K. Landas, Andrew H. Cragg, Steve C. De Jong, Theodore Gleason |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Iliac artery
medicine.medical_specialty Mongrel dogs business.industry medicine.medical_treatment Balloon Elastic recoil Dogs Evaluation Studies as Topic Internal medicine Angioplasty medicine Cardiology Animals Radiology Nuclear Medicine and imaging Cardiology and Cardiovascular Medicine Nuclear medicine business Saline Canine model Angioplasty Balloon |
| Zdroj: | Journal of Vascular and Interventional Radiology. 1:121-126 |
| ISSN: | 1051-0443 |
| Popis: | Preliminary results suggest that thermal balloon angioplasty (BA) may produce plaque welding, decreased elastic recoil, and increased luminal caliber. The authors report results of a simple method of thermal BA in a canine model. Seven mongrel dogs (15-25 kg) underwent conventional BA of each iliac artery with balloons that were 1-2 mm larger than the vessel lumen. The balloons were then perfused with a mixture of saline and contrast material at either 25 degrees C (control) or 100 degrees C for 1 minute. Compared with baseline measurements, thermal BA produced greater lumen enlargement (+16.7%) than control BA (+3.4%) immediately after the procedure (P less than .05). This trend persisted in vessels studied after a delay of 2, 4, or 12 weeks. Histologic sections from specimens studied after a delay demonstrated intimal hyperplasia in both the thermally treated and control arteries. Medial sclerosis was consistently seen in the thermally treated arteries. The authors conclude that thermal BA results in immediate and delayed increases in arterial diameter compared with conventional BA due to decreased elastic recoil and medial sclerosis. |
| Databáze: | OpenAIRE |
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