Assessment of autonomic nervous system using analysis of heart rate variability in young smokers and non-smokers
| Autor: | Matija Fenrich, Dunja Vujčić, Matej Šapina, Katarina Badak, Dinko Puntarić, Marko Pirić, Dario Brdarić |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry media_common.quotation_subject Significant difference Abstinence Nicotine Autonomic nervous system Internal medicine Heart rate Cardiology Medicine Heart rate variability Assessment autonomic nervous system heart rate variability young smokers non-smokers Spectral analysis business Sympathetic tone media_common medicine.drug |
| Popis: | The effect of nicotine is complex and most of the research of the heart rate variability is done with tobacco in participants trying to cease smoking. Such studies are limited with desensitization of nicotinic receptors, emergence of abstinence symptoms, and the overall modified activation of the autonomic nervous system. The aim of this study is to show the effect of nicotine on young smokers and nonsmokers using descriptive and spectral analytical methods of the heart rate variability. The research was conducted on 50 participants (m=23, f=27), average age of 21.8±1.49 years, who were divided into nonsmokers (n=26, m=11, f=15) and smokers (n=24, m=12, f=12). Smokers were smoking 14.8±6 cigarettes on average for 4.77±2.19 years. A baseline ECG lasting 100s was recorded, followed by chewing a gum containing 4 mg of nicotine, after which an ECG lasting 100 s was re-recorded. The ECG analysis was followed by the analysis of the heart rate variability using time domain and frequency domain methods. In order to show the effects of nicotine more precisely, the resulting changes (Δn) were calculated as the difference between the final and initial values of variables, after which the changes (Δn = T2-T1) were statistically compared between smokers and nonsmokers. After the application of nicotine, a significant difference was observed in the changes of the average length of the RR intervals (p=0.01) and the heart rate (p |
| Databáze: | OpenAIRE |
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