Treatment of adult patients with schizophrenia and complex mental health needs - A national clinical guideline
| Autor: | Susanne Voss-Knude, Vilhelm Schultz, Thomas Bjørnshave, Jens Peter Hansen, Louise Klokker, Merete Nordentoft, Karl Erik Sandsten, Lone Baandrup, Vibeke Bliksted, Jesper Østrup Rasmussen, Stephen F. Austin, Allan Fohlmann, Malene Nielsen, Anders Fink-Jensen |
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| Rok vydání: | 2015 |
| Předmět: |
Family therapy
medicine.medical_specialty Substance-Related Disorders Denmark Psychological intervention Health Services Accessibility law.invention 03 medical and health sciences 0302 clinical medicine Randomized controlled trial law medicine Humans Psychiatry Clinical guideline quality of evidence Evidence-Based Medicine Cognitive Behavioral Therapy business.industry Evidence-based medicine Guideline Mental health 030227 psychiatry meta-analysis schizophrenia Psychiatry and Mental health GRADE Systematic review Treatment Outcome Diagnosis Dual (Psychiatry) Meta-analysis Schizophrenia strength of recommendations Family Therapy business 030217 neurology & neurosurgery Antipsychotic Agents |
| Zdroj: | Baandrup, L, Østrup Rasmussen, J, Klokker, L, Fitzgerald Austin, S, Bjørnshave, T, Fuglsang Bliksted, V, Fink-Jensen, A, Hedegaard Fohlmann, A, Peter Hansen, J, Nielsen, M K, Sandsten, K E, Schultz, V, Voss-Knude, S & Nordentoft, M 2016, ' Treatment of adult patients with schizophrenia and complex mental health needs : A national clinical guideline ', Nordic Journal of Psychiatry, vol. 70, no. 3, pp. 231-240 . https://doi.org/10.3109/08039488.2015.1074285 Baandrup, L, Østrup Rasmussen, J, Klokker, L, Austin, S, Bjørnshave, T, Fuglsang Bliksted, V, Fink-Jensen, A, Hedegaard Fohlmann, A, Peter Hansen, J, Kristine Nielsen, M, Sandsten, K E, Schultz, V, Voss-Knude, S & Nordentoft, M 2016, ' Treatment of adult patients with schizophrenia and complex mental health needs-A national clinical guideline ', Nordic Journal of Psychiatry, vol. 70, no. 3, pp. 231-240 . https://doi.org/10.3109/08039488.2015.1074285 |
| ISSN: | 1502-4725 |
| DOI: | 10.3109/08039488.2015.1074285 |
| Popis: | Background and aim: The Danish Health and Medicines Authority assembled a group of experts to develop a national clinical guideline for patients with schizophrenia and complex mental health needs. Within this context, ten explicit review questions were formulated, covering several identified key issues. Methods: Systematic literature searches were performed stepwise for each review question to identify relevant guidelines, systematic reviews/meta-analyses, and randomized controlled trials. The quality of the body of evidence for each review question was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system. Clinical recommendations were developed on the basis of the evidence, assessment of the risk-benefit ratio, and perceived patient preferences. Results: Based on the identified evidence, a guideline development group (GDG) recommended that the following interventions should be offered routinely: antipsychotic maintenance therapy, family intervention and assertive community treatment. The following interventions should be considered: long-acting injectable antipsychotics, neurocognitive training, social cognitive training, cognitive behavioural therapy for persistent positive and/or negative symptoms, and the combination of cognitive behavioural therapy and motivational interviewing for cannabis and/or central stimulant abuse. SSRI or SNRI add-on treatment for persistent negative symptoms should be used only cautiously. Where no evidence was available, the GDG agreed on a good practice recommendation. Conclusions: The implementation of this guideline in daily clinical practice can facilitate good treatment outcomes within the population of patients with schizophrenia and complex mental health needs. The guideline does not cover all available interventions and should be used in conjunction with other relevant guidelines. |
| Databáze: | OpenAIRE |
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